Kevin Spacey in the film 21

The gambling drama 21 won big at the US box office last weekend, earning $23.7 million in its opening three days to top the chart. The film stars Kevin Spacey - Kate Bosworth and Jim Sturgess as maths geniuses who adapt their skills to the blackjack tables of Las Vegas. It is loosely based on Ben Mezrich’s non-fiction bestseller Bringing Down the House: The Inside Story of 6 MIT Students Who Took Vegas For Millions.

Kevin Spacey in the film 21.

There was also good news for last week’s winner - Horton Hears a Who!. The family comedy may have slipped to second place, but its weekend gross of $17.4m made it the first film of 2008 to cross the $100m mark in overall takings.

The comic-book spoof Superhero Movie was a new entry at three with $9.5m, while Stop Loss, Kimberley Peirce’s acclaimed tale of army deserters - entered the chart at number eight - having earned $4.5m on a limited release.

Run - Fat Boy, Run grossed a disappointing $2.4m to debut in 10-th place. The London-set comedy, starring Simon Pegg and Thandie Newton, was a box office number one in the UK last year, but has met with stinging reviews for its belated US release.

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